# Statistics in Medicine (Self Paced 16')

Date:
Sunday, February 28, 2016
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Course topic:

Welcome to the self-paced version of Statistics in Medicine! The course is organized into 9 learning units that contain videos, quizzes, and a homework assignment. You may complete these at any pace. At the end of the course, there is a multiple-choice final exam. Once you have completed the course, if you have earned at least 60% on the graded assignments, you will be able to request a Statement of Accomplishment (users who score 90% or higher will earn a Statement of Accomplishment with Distinction). Course enrollment and the materials and assignments will be open until at least April, 2017. If access to the course materials will be turned off at any point, notification will go out to all course participants.

This course aims to provide a firm grounding in the foundations of probability and statistics. Specific topics include:

1. Describing data (types of data, data visualization, descriptive statistics)
2. Statistical inference (probability, probability distributions, sampling theory, hypothesis testing, confidence intervals, pitfalls of p-values)
3. Specific statistical tests (ttest, ANOVA, linear correlation, non-parametric tests, relative risks, Chi-square test, exact tests, linear regression, logistic regression, survival analysis; how to choose the right statistical test)

The course focuses on real examples from the medical literature and popular press. Each unit starts with "teasers," such as: Should I be worried about lead in lipstick? Should I play the lottery when the jackpot reaches half-a-billion dollars? Does eating red meat increase my risk of being in a traffic accident? We will work our way back from the news coverage to the original study and then to the underlying data. In the process, participants will learn how to read, interpret, and critically evaluate the statistics in medical studies.

The course also prepares participants to be able to analyze their own data, guiding them on how to choose the correct statistical test and how to avoid common statistical pitfalls. Optional modules cover advanced math topics and basic data analysis in R.

## COURSE SYLLABUS

Unit 1 - Descriptive statistics and looking at data
Unit 2 - Review of study designs; measures of disease risk and association
Unit 3 - Probability, Bayes' Rule, Diagnostic Testing
Unit 4 - Probability distributions
Unit 5 - Statistical inference (confidence intervals and hypothesis testing)
Unit 6 - P-value pitfalls; types I and type II error; statistical power; overview of statistical tests
Unit 7 - Tests for comparing groups (unadjusted); introduction to survival analysis
Unit 8 - Regression analysis; linear correlation and regression
Unit 9 - Logistic regression and Cox regression

## PREREQUISITES

There are no prerequisites for this course.

Participants will need to be familiar with a few basic math tools: summation sign, factorial, natural log, exponential, and the equation of a line; a brief tutorial is available on the course website for participants who need a refresher on these topics, and can also be found here.

## COURSE STAFF

### Kristin Sainani

Kristin Sainani (née Cobb) is an associate professor at Stanford University. She has taught statistics and writing at Stanford for more than a decade and has received several Excellence in Teaching Awards from the graduate program in epidemiology. She received her MS in statistics and her PhD in epidemiology from Stanford University; she also received a certificate in science writing from the University of California, Santa Cruz.

Dr. Sainani specializes in teaching and writing about science and statistics. She is the statistical editor for the journal Physical Medicine & Rehabilitation; and she writes a statistics column, Statistically Speaking, for this journal. She also authors the health column Body News for Allure magazine; and she writes about health and science for a variety of other publications. In addition to this MOOC, she has taught the MOOC "Writing in the Sciences" on Coursera and Stanford Online.

### Joshua Wallach (TA)

Joshua Wallach graduated with a Bachelors degree in Economics from the University of California, Davis in 2012. As a current PhD student in Epidemiology and Clinical Research, he is interested in evaluating statistical and epidemiological methods, identifying and minimizing biases, and promoting reproducibility of research. Joshua is passionate about the interdisciplinary nature of epidemiology and meta-research and enjoys working as a Teaching Assistant. When not busy pursuing an academic career, Joshua loves living in Oakland and enjoys hiking, playing guitar, and working out.

### Michael McAuliffe (Instructional Technologist)

Mike McAuliffe is an Instructional Technologist in EdTech, IRT for the Stanford University School of Medicine. He supports a wide range of educational technology operations, projects, and initiatives in support of teaching, learning, and research.

Mike joined the School of Medicine in August 2012 and dedicates the majority of his time to the Stanford Medicine Interactive Learning Initiative (SMILI). In this role, Mike collaborates with SoM faculty to design and produce video content for online/hybrid courses delivered to undergraduate medical education, online courses for continuing medical education, online materials for residents and fellows, and MOOCs. Mike also provides instructional design, graphic design, and project planning support to faculty.

### Will I get a Statement of Accomplishment?

Yes, participants who score at least 60 percent will pass the course and receive a Statement of Accomplishment.

Participants who score at least 90 percent will receive a Statement of Accomplishment with Distinction.

### How much of a time commitment will this course be?

The course consists of 9 units and each unit will take approximately 8 - 12 hours to complete, but you can work through all of the material at your own pace and on your own schedule. There are no due dates for any of the assignments.